BioPure case :: essays research papers

BioPure Corporation, which was founded in 1984 by entrepreneurs Carl Rausch and David Judelson, is a privately owned biopharmaceutical firm specializing in the ultra purification of proteins for human and veterinary use. In 1998 Biopure pioneered the development of oxygen therapeutics using â€Å"Hemoglobin†, a new class of pharmaceuticals that are intravenously administered to deliver oxygen to the body's tissues. Biopure's two products, Hemopure for human use, and Oxyglobin for animal veterinary use, both represented a new Oxygen based treatment approach for managing patients' oxygen requirements in a broad range of potential medical applications. The factor distinguishing Biopure’s two products from other blood substitute products being developed by two possible rivals, Baxter International and Northfeild Laboratories, is that its hemoglobin based source is bovine rather than human and was derived from the blood cells of cattle. Both of Biopure’s blood substi tute products were in the final stages of the approval process of the Food and Drug Administration (FDA) in 1998. Oxyglobin had just received the FDA’s approval for commercial release declaring it safe and effective for medical use. Hemopure was entering final Phase 3 clinical trials and was optimistically expected to see final FDA approval for release in 1999. The FDA approval of Oxyglobin and its possible subsequent release into the veterinary market caused concern over whether the early release of Hemoglobin would impinge BioPure’s ability to price Hemopure when the product finally received approval. Given that the two products were almost identical in properties and function, it was thought that the early release of Oxyglobin would create an unrealistic price expectation for Hemopure if released first. Although blood transfusions in the veterinary market are infrequent and the market scope is limited, Oxyglobin has the potential to become a lucrative investment for Biopure. Based on the approximate 355,000 blood transfusions (please see Exhibit 1 for the calculations behind this estimate) performed on animals in 1995, a definite opportunity exists for Oxyglobin within the veterinary blood market. Since the number of blood transfusions conducted in 1995 represented on average only 2.5% of animals suffering from acute blood loss, increased availability of animal blood could possibly stimulate the market.   Ã‚  Ã‚  Ã‚  Ã‚  In order to estimate the possible impacts of introducing Oxyglobin as a major product, it was assumed that Biopure would be able to produce and sell its full capacity of 300,000 units per year. As can be seen in Exhibit 1, the results of such an aggressive marketing strategy would yield a positive gross margin of between 49% and 66%, assuming the product was sold at a price of $100 to $150 per unit.

The Joy and Pain of Raising a Child with Special Needs

The Joys and Pain Of Raising A Child With Special Needs Donna McFadden ENG121 English Composition I Mr. Jonathan Alexander, Instructor February 18, 2013 The Joys and Pain Of Raising A Child With Special Needs Even though I am not the only parent of a child of special needs this is my personal journey into the world of special needs. No one could have told me that at the age of forty three I would be experiencing motherhood again to a child born with Cerebral Palsy. In fact, I was just preparing to celebrate my 25th high school reunion when I got the news that I was pregnant.When faced with the complex challenges of single motherhood you will soon find out that love is all you need. Allow me to give my account of this life altering phenomenon that totally changed the course of my mindset and direction in life. After an extremely emotional pregnancy and delivery by C-section, my son Nathan took his first breaths into a world of chaos and confusion. Being rushed to the neo-natal intensi ve care unit weighing only 4 lbs 3 oz, being probed and pricked by doctors and nurses to help stabilize the very life he stepped into.The thoughts of what my little angel endured coming into this world shows me his strength and determination as he begins his fight on this journey to manhood. Life began for my son spending his first few weeks of life in a NICU as they call it in the hospital with incubators and feeding tubes combined with the constant care from doctors and nurses assigned to his care. How traumatic for both mother and child to experience the separation and disconnect that is being substituted by machines. I forced the hospital to allow me an opportunity to stay in a room so that I could be as close to my son as I could.I was there for every feeding, every diaper change, all the testing I would sit in the NICU beside his bed and sing to him to reassure him that I was there. I was determined to be with my child as much as I could through this torturous ordeal. The inst ructions that we had to follow when we got home were intense, because of his prematurity and low birth weight many important things were still developing. I had numerous classes and seminars that I had to attend and complete before leaving the hospital. I even had to purchase a new car seat because the one that I had was not sufficient for a premature child.We immediately began having to parade through doctors offices on a weekly basis to be tested and examined and this process required a lot of patience and dedication. At five months olds we were back in the hospital so that Nathan would have his first surgery to repair three hernias. Once he recuperated it was then time for the next round of surgeries and this rollercoaster ride seemed to go on for months. Throughout this process you’re trying to find those opportunities to enjoy your child, those memorable moments of accomplishments and milestones.During these months I had no idea my son has Cerebral Palsy, nor had I ever experienced anyone who had been diagnosed with this disability. When we got the diagnoses of Cerebral Palsy, Nathan was fourteen months old and a very happy, determined little toddler, actually to look at him you would never know that he had brain damage. For me, not really knowing what it meant to have Cerebral Palsy actually played to my advantage because I didn’t have an opportunity to get upset, but more of a determination to educate myself on what I needed to do to help this baby grow into a wonderful productive person.Just like when he was born we were thrown into the arena of occupational therapy, physical therapy, speech therapy more doctors and test after test after test. This process is extremely daunting, however necessary. I was just trying to tackle each obstacle as it came day-by-day with all the optimism I could muster. I had a determination to not think negatively or get in that place of despair or asking â€Å"why me? † How do you balance the range of emotions that not only go through your mind, but the minds of your family and friends about the hopes and fears of the destiny of your child?I am so grateful for my faith and belief system to help me sustain my strength and emotional well-being because I have no idea where I would be without it. This was truly one of the most difficult times of my life combined with an element of gratitude for the life and well-being of my son. Even though we are still on this journey a lot of progress has been made from that first day of life in July. My positive attitude about my son’s disability has been engraved in him and I am quite encouraged that through it all he will be such a positive example of how the challenges of Cerebral Palsy will not dictate his life.

Kant And Sir William David Ross Essay - 1011 Words

Immanuel Kant and Sir William David Ross agreed and disagreed about different aspects of ethical practice. Both philosophers had influential views on ethics with strong opinions and interpretations of what moral philosophy is. Part of C.S. Lewis’ Book touches on the notions raised by the philosophers. Positions of Kant and Ross Immanuel Kant was a Rule Nonconsequentialist Theorist who established Duty Ethics. His theory stemmed from the idea of moral absolutism, a theory which believes moral truths are absolute and we must adhere to them no matter the situation or individuals involved. Kant argued moral requirements are based on a standard of rationality he coined the Categorical Imperative. He surmised immorality requires a violation of the Categorical Imperative and therefore is unreasonable. (Thiroux and Krasemann, pg. 78). Sir William David Ross agreed with Kant’s Rule Nonconsequentialist Theory but not from the absolutism Kant derived the theory from. He believed in the notion of prima facie duties, which basically states we have certain duties which we must adhere to no matter the situation (Thiroux and Krasemann, pg. 54). In turn, he can be considered a theorist in-between Kant and rule utilitarians since he is a Rule Nonconsequentialist Theorist but based on relativity rather than absolutism. Summary of Lewis’, What Christians Believe Lewis’ â€Å"What Christians Believe† is divided into five distinct parts, each attempting to defend the existence of God. The RivalShow MoreRelatedEssay on Deontologial Theory1295 Words   |  6 Pagesdivine revelation.  §nbsp;nbsp;nbsp;nbsp;nbsp;The consequential ethical theory of Bentham theorized that the consequences of one’s behavior are crucial when making moral decisions.  §nbsp;nbsp;nbsp;nbsp;nbsp;The non-consequential ethics of Kant which viewed an individual’s duty and moral obligation as paramount when faced with an ethical challenge. Contemporary philosophers define ethics as a philosophical examination of the principles of right versus wrong, and view morality as the practiceRead MoreNormative Theories Of Ethics And Its Principles2769 Words   |  12 Pagesformalistic in nature because of the main principle affecting the conformity of action to a certain rule or law. It was Immanuel Kant (1724-1804), in the 18th century, German by origin and the first philosopher to define deontological principles. Kant was also the proponent of critical philosophy and an opponent of utilitarianism. According to the theories established by Immanuel Kant the followed are principles are highlighted: Categorical Imperative: Act only on that maxim whereby you can at the sameRead MoreInterview And Staff Of The Alligator1840 Words   |  8 Pagesfocus is on treating others as one would treat themselves and specifically not treating others as a means to an end. Moreover, Kant does not believe any ends can justify any means. In this case, the end goal is too better inform the audience of the situation and what can be learned from it, and the means involve exposing a disturbing or even distasteful image to the public. Kant would not approve of the use of the offensive image. In contrast, John Stuart Mill finds that a desirable end is the mostRead MoreSources of Ethics20199 Words   |  81 Pages55 2.31- Contribution Of In Ethics By The Source Of Philosophical Systems: 55 2.32- Contribution of Aristotle: 57 2.33- Contributions By Other Important Philosophers: 58 2.34- Rights Theory: 64 2.35- Contribution By KANT: 65 2.36- Contribution By ROSS: 66 2.4- CULTURAL: 68 2.5- LEGAL SYSTEM: 71 2.6- CODES OF ETHICS: 74 2.61- Company Codes: 74 Code of ethics (corporate or business ethics) 74 code of ethics(business of ethics) 75 Code of conduct (employee ethics)Read MoreOrganisational Theory230255 Words   |  922 Pageslike to acknowledge the contribution of many others to its development. We would like to express our thanks to Jacqueline Senior, who was our original commissioning editor, and to Matthew Walker, who took over that role. We also would wish to thank David Cox and Stuart Hay, who have been our development editors. Their contribution to the pedagogic shaping of the text challenged many of our initial assumptions about the nature of a ‘textbook’ on organization theory and have enabled us to produce what